From the North:

If you're coming from Detroit, Indianapolis,
Cincinnati or Lexington, take I-75 to Knoxville. Take I-40 east
to exit 407. Turn right onto S.R. 66. Continue until the first
major intersection in Sevierville. Turn left onto U.S. 411 and
follow 411 to S.R. 416. Turn right on S.R. 416 and follow until
you reach U.S. 321. Turn right onto U.S. 321 south and west
and continue until you reach Gatlinburg. Continue through Gatlinburg.
From light #1, it is less than a mile to the Park entrance and
the Sugarland Visitors Center.
From the Northeast:
If you are coming from Harrisburg and Roanoke,
take I-81 south to I-40 east. Take I-40 to Wilton Springs/U.S.
321 south and west exit 440. Turn right and follow U.S. 321
into Gatlinburg. From light #1, it is less than a mile to the
Park entrance and the Sugarland Visitors Center.
If you are coming from Baltimore and Washington
D.C., take I-66 to I-81 southand then to I-40 east. Take I-40
to Wilton Springs/U.S. 321 south and west exit 440. Turn right
and follow U.S. 321 into Gatlinburg. From light #1, its less
than a mile to the Park entrance and the Sugarland Visitors
Center.
From the Northwest
If you are coming from Mikwaukee and Peoria,
take I-65 to I-40 east to the 407 exit. Turn right onto S.R.
66. Continue until the first major intersection in Sevierville.
Turn left onto U.S. 411 and follow 411 to S.R. 416. Turn right
on S.R. 416 and follow until you reach U.S. 321. Turn right
onto U.S. 321 south and west and continue until you reach Gatlinburg.
Continue through Gatlinburg. From light #1, it is less than
a mile to the Park entrance and the Sugarland Visitors Center.
From the East
If you are coming from Richmond, Charlotte,
Raleigh, Greensboro and Winston-Salem, take I-85 to I-40 west.
Take I-40 west to the Foothills Parkway exit 443. Turn left
onto U.S. 321. Follow U.S. 321 until you reach Gatlinburg. Continue
through Gatlinburg. From light #1, it is less than a mile to
the Park entrance and the Sugarland Visitors Center.
From the Southeast
If you are coming from Tampa, Montgomery, Birmingham,
Macon, Atlanta and Chattanooga, the quickest route is to take
I-75 to exit 81 (S.R.95). Go east on 321 through Maryville and
Townsend. where you enter the Park from the Townsend entrance,
near Cades Cove. Optionally, if you are in the upper reaches
of Georgia and North Carolina, you can enter the Park at the
south entrance at Cherokee, NC via 441 at Dillsboro.
If you are coming from Charleston, Columbia,
Greenville, Spartanburg, Asheville, Jacksonville, Miami and
Daytona Beach, take I-26 to I-40 west and the Foothills Parkway
exit 443. Turn left onto U.S. 321. Follow U.S. 321 until you
reach Gatlinburg. Continue through Gatlinburg. From light #1,
it is less than a mile to the Park entrance and the Sugarland
Visitors Center.
From the Southwest
If you are coming from Tulsa, Little Rock and
Memphis, take I-40 east to exit 364 S.R. 95. Go east on 321
through Maryville and Townsend. where you enter the Park from
the Townsend side of the Smokies, near Cades Cove.
(Biloxi, Gulfport and Mobile): Take I-65
to I-85 and I-75 north. Continue on I-75 north to exit 364 S.R.
95. Go east on 321 through Maryville and Townsend. where you
enter the Park from the Townsend side of the Smokies, near Cades
Cove.
From the West:
If you are coming from Witchita, Kansas City,
St. Louis and Nashville, take I-70 to I-64 (through St. Louis).
Continue I-64 to I-57 to I-24 and the I-40 east (through Nashville).
Stay on I-40 east and exit 364 S.R. 95. Go east on 321 through
Maryville and Townsend. where you enter the Park from the Townsend
side of the Smokies, near Cades Cove.
NOTE: During the winter months, weather
conditions can close the Foothills Parkway. If in doubt, call
the Park. If the Foothills Parkway is closed, take I-40 to exit
440 to S.R. 32 and U.S. 321 through Gatlinburg to enter the
park.
During the summer months, construction and
repairs are often being accomplished on the routes described
above. You should call the Tennessee Department of Transportation
or stop at the visitor's centers when entering Tennessee to
request an update and map showing where construction or repair
might cause traffic delays.